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| Product ID | JR8-N1235 |
| Product Name | Epiberberine (New Product) |
| CAS # | 6873-09-2 |
| Structure |  |
| Molecular Formula | C20H18NO4+ | | Molecular Weight | 336.36 | | Chemical Purity | 98% (HPLC) |
| Price | $198/20mg, $518/100mg, 500mg, 1g, 5g |
| Comments | Epiberberine, a natural protoberberine alkaloid, is a potent inhibitor against both ureases with IC50 values of 3.0±0.01ìM for HPU (ureases from Helicobacter pylori) and 2.3±0.01ìM for JBU (ureases from jack bean); it also exhibits predominant cholinesterases (ChEs) inhibitory effects with IC(50) values ranging between 0.44-1.07 microM for AChE and 3.32-6.84 microM for BChE. Epiberberine has anti-adipogenic effect is mediated by downregulation of the Raf/MEK1/ERK1/2 and AMPKá/Akt pathways during 3T3-L1 adipocyte differentiation. Epiberberine also ha anti-alzheimer and antioxidant activities. |
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