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| Product ID | JR8-N0645 |
| Product Name | Eupatilin (New Product) |
| CAS # | 22368-21-4 |
| Structure |  |
| Chemical Purity | 98% | | Appearance | Yellow crystal |
| Price | $268/100mg, $880/500mg, $1280/1g, $3980/5g, $5980/10g |
| Comments | Eupatilin, a flavone derived from Artemisia princepsPampanini, has various pharmacological activities, including antioxidant, anti-tumor, and anti-inflammatory capacities.
IC50 value:
Target:
In vitro: The present study aimed to investigate the effects of eupatilin on this malignant bone tumor, using the U-2 OS cell line. The experimental results revealed that eupatilin inhibited U-2 OS cell growth in a concentration-dependent manner and induced G2/M phase cell cycle arrest and apoptosis [1]. Eupatilin reduced U937 cells adhesion to TNF-á-stimulated HUVECs and attenuated TNF-á-induced the expression of vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) in HUVECs, as well as the production of intracellular reactive oxygen species (ROS). Moreover, eupatilininhibits TNF-á-induced phosphorylation of NF-kB p65 and MAPKs in HUVECs [2].
In vivo: |
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