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Product ID | JR8-N0238 |
Product Name | (-)-Gallocatechin gallate |
CAS # | 4233-96-9 |
Structure | |
Chemical Purity | 98% |
Price | $198/20mg, $518/100mg, $1480/500mg, $2480/1g, 5g |
Comments | (–)-Gallocatechin gallate ((–)-GCG) is a catechin polyphenol that has been found in oolong tea stems and green tea extracts with diverse biological activities. It inhibits histamine release from anti-egg albumin (EA) IgE antibody-sensitized rat peritoneal mast cells when used at concentrations ranging from 0.1 to 1 mg/ml.1 (–)-GCG reduces proliferation of MDA-MB-231 breast cancer cells (IC50 = 22 ìg/ml) and human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner. It also inhibits human placental aromatase activity (IC50 = 15 ìM). (–)-GCG is lytic against T. cruzi amastigotes, with a 50% bactericidal concentration (MBC50) value of 0.12 pM. It also decreases RAW 264.7 osteoclastogenesis when used at a concentration of 20 ìM. |
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