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Product IDJR8-N0208
Product NameCostundide (New Product)
CAS #553-21-9 
Structure
Chemical Purity98% 
AppearanceWhite powder 
Price $148/100mg, $580/500mg, $980/1g 
CommentsCostunolide has antipyretic, anti-inflammatory, anti-oxidant, anti-carcinogenic and anti-fungal activities, it possesses normo-glycemic and hypolipidemic activity. Costunolide inhibits RANKL-induced osteoclast differentiation by suppressing RANKL-mediated c-Fos transcriptional activity; it inhibits IL-1beta gene expression by blocking the activation of MAPKs and DNA binding of AP-1; it also induces the ROS-mediated mitochondrial permeability transition and resultant cytochrome c release, 
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