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Product ID | JR8-N0046 |
Product Name | Sinomenine (HCl) (New Product) |
CAS # | 6080-33-7 (115-53-7) |
Structure | |
Chemical Purity | 98% |
Price | $188/10g, $498/100g |
Comments | 1. Sinomenine exerts significant antinociceptive effects for neuropathic pain via GABAa-mediated mechanism.
2. Sinomenine shows a significant neuroprotective effects against both LPS- and MPP+-induced DA neurotoxicity, and that this protection is mediated through microglia.
3. Sinomenine inhibits cerebral water content and neurological deficit, can be used to treat Alzheimer's diseases as well as other diseases that involve neuroinflammation.
4. Sinomenium is widely used as an immunosuppressive drug for treating rheumatic and arthritic diseases via release of histamine, but other effects such as inhibition of prostaglandin, leukotriene and nitric oxide synthesis may also be involved. |
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