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Product ID | JR8-N1238 |
Product Name | Diammonium glycyrrhizinate (New Product) |
CAS # | 79165-06-3 |
Structure | |
Chemical Purity | 98% (HPLC) |
Price | $268/100mg, $880/500mg, $1280/1g |
Comments | Diammonium glycyrrhizinate shows antiviral, and anti-inflammatory effects, it can reduce inflammatory injury in a rat model of ulcerative colitis, this may occur via suppression of NF-kappaB, TNF-alpha and ICAM-1 in colonic mucosa. Diammonium glycyrrhizinate may possibly protect the liver from injury via two pathways: direct protection of hepatocytes from apoptosis through an IL-6-dependent way and indirect inhibition of T-cell-mediated inflammation through an IL-10-dependent way. Diammonium glycyrrhizinate exerts potential beneficial effects on Alzheimer's disease, it can attenuate Aâ(1-42)-induced neuronal injury by preventing mitochondrial dysfunction and oxidative stress and improve cognitive impairment in Aâ(1-42)-induced AD mice.Diammonium glycyrrhizinate also can inhibit airway smooth muscle proliferation possibly through up- regulation of PPARã in a murine model of chronic asthma. |
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