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| Product ID | JR8-N0208 |
| Product Name | Costundide (New Product) |
| CAS # | 553-21-9 |
| Structure | |
| Chemical Purity | 98% | | Appearance | White powder |
| Price | $148/100mg, $580/500mg, $980/1g |
| Comments | Costunolide has antipyretic, anti-inflammatory, anti-oxidant, anti-carcinogenic and anti-fungal activities, it possesses normo-glycemic and hypolipidemic activity. Costunolide inhibits RANKL-induced osteoclast differentiation by suppressing RANKL-mediated c-Fos transcriptional activity; it inhibits IL-1beta gene expression by blocking the activation of MAPKs and DNA binding of AP-1; it also induces the ROS-mediated mitochondrial permeability transition and resultant cytochrome c release, |
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