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Product ID | JR8-N0039 |
Product Name | Genistein |
CAS # | 446-72-0 |
Structure | |
Chemical Purity | 98% |
Price | $98/100mg, $398/500mg, $518/1g, 5g |
Comments | Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12ìM or by insulin with IC50 of 19 ìM. Genistein has neuroprotective, antitumor effects, it modulates the expression of NF-êB and MAPK (p-38 and ERK1/2), thereby attenuating d-Galactosamine induced fulminant hepatic failure in Wistar rats. |
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